CBD displays a promising future for the world of natural medicine. Scientists continue their pursuit of gaining more information as to how powerful this wonder substance is.
Cannabidiol (CBD) is one of the many compounds found in the family of Cannabis Sativa plants. It does not bind with your cannabinoid receptors that’s why it would not put you in a state of euphoria.
The endocannabinoid system (ECS) in the body absorbs CBD and helps the body react to it in a positive way. CBD helps your health in many ways because of its analgesic, anti-inflammatory, and antioxidant properties, among others.
Another powerful substance that you can find in cannabis is tetrahydrocannabinol or THC. It could also help you with pain management.
But unlike CBD, THC binds with the CB1 and CB2 receptors, thus the “kick.” It imitates anandamide, a neurotransmitter that emits the sensation of delight. If you’re thinking why chocolate makes you happy, anandamide is the culprit.
Now, what if we combine CBD and THC in one medication? Would it be a disaster? Let’s find out.
Understanding Entourage Effect
Before getting straight into business, you need to know the different types of CBD in the market:
- Broad-spectrum CBD products are those that contain everything there is in a full-spectrum CBD except for THC.
- Full-spectrum CBD products are those that have the natural ingredients of hemp. These components are fatty acids, terpenes, other cannabinoids, flavonoids, and a small amount of THC. The legal amount is 0.3% in the United States.
- CBD Isolate products are those that only have pure CBD and nothing else.
If you use Broad-spectrum CBD and Full-spectrum CBD products, you’d feel the entourage effect. You could say that it is a perfect combination since THC with CBD is equivalent to a lesser kick. Instead, you would feel more balanced.
Let’s have an example. If you use THC alone, you may feel anxious and stoned. But when you combine it with CBD, THC’s bind with the CB1 receptor becomes weak.
The History of Entourage Effect
A decade ago, a doctor name Ethan Russo used the term “entourage effect” on his paper about taming THC. In his theory, he stated that the synergy between cannabinoids and terpenes work perfectly together.
This synergy even produces effects way different than when THC is solely used. It is not limited to the compounds you already know. It’s about all the great nutrients you could get from the whole plant – even the essence.
The entourage effect is not just limited to the combination of CBD and THC. One popular combo is between terpenes and cannabinoids.
Instead of making you feel high, you’d actually feel more energetic and inspired with this entourage effect. There is a huge web of possibilities when you consider using cannabis compounds.
In 2011, a review showed a huge potential when combining THC and alpha pinene. The latter helps in memory formation. Therefore, THC’s short-term memory loss side effect can be controlled if mixed with alpha pinene.
Another example is the combination of pinene with caryophyllene and myrcene. The result: the mix helps combat anxiety.
You may also consider CBD plus limonene and linalool. The effect is perfect for treating acne.
There are so many possible combinations with the hundreds of cannabinoids out there. We just need further studies to confirm the positive effects of these synergies.
Your Choice of Effect
Now, going back to your choices. If your goal is to get the entourage effect, you’d definitely not focus on using products that are CBD isolates. It is the usual option for those who would rather enjoy the benefits of CBD alone.
If you think it is not enough for your need yet you want to play it safe, you may want to consider products with broad-spectrum CBD.
In the CBD and THC combination, the compound with the biggest influence is CBD as it calms down THC’s euphoric effect. In a test done in 2010, equal amounts of CBD and THC were given to patients.
Out of 250 exposures, only four experienced psychoses. Scientists admit that there’s still a long way to go, but this development surely adds to the growing number of natural health options.
Doubts About the Entourage Effect
Of course, if there are believers, there are doubters. Just recently, researchers tested THC on cells of a rat of which they placed CB1 and CB2 receptors.
The cells got exposed to THC for a long time, resulting in hyperpolarization. It means that there was a negative change that happened to the cell.
The test was repeated, this time with six terpenoids included. The added compounds did not do anything significant; the cells still hyperpolarized.
However, this test was done in rat cells, unlike in Dr. Russo’s research with humans showing positive results. Definitely, the people behind the research need more experiments to confirm or disprove any theory.
Verdict: The Future of Synergies
Now that the Farm Bill is in effect, many researchers continue their quest to discover all possibilities. It is indeed promising, with the amazing results scientists revealed over the years.
If you think that THC is something you would need to think about, then just focus on CBD isolates. I am not saying that they are ineffective; pure CBD has its own promise.
However, if you would like to explore in response to your health needs, you may want to try a balanced mix of CBD and THC, along with other helpful cannabinoids and terpenes. Of course, this choice comes with a risk.
But what’s great about it is that the world is now exposed to other healthy options. We are not stuck with just synthetic medication.
Just like me, you aim for natural alternative medicine. People talk about cannabis more openly than in the past; thanks to the benefits actual users are sharing to the world.
A lot of studies are yet to be proven; more scientific tests need to be done. But what’s great is that information is just one click away.
There are so many articles about CBD and THC individually. We already know what each could do alone. If they are already good on their own, they would definitely be awesome together.
We no longer live in rumors; we want straight facts. With our goal to live a healthy lifestyle, we explore and become more open to a whole new world of endless possibilities.